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Amino acid residues in the glucagon (GCGR), GLP-1 (GLP1R), and GLP-2 (GLP2R) receptor protein sequences that interact with the proglucagon-derived peptides are from sites identified in crystal structures and were retrieved from the GCPRdb (gpcrdb.org) (6266)

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Hormones and therapeutics that act in part via the hypothalamus have made tremendous waves in the past year, underscoring the importance of endocrine regulation in the pathophysiology and treatment of prevalent metabolic disorders such as obesity, diabetes, and fatty liver disease, Abel concludes

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